publication . Article . 2004

Rotavirus typing methods and algorithms

Thea K. Fischer; Jon R. Gentsch;
Open Access English
  • Published: 01 Feb 2004 Journal: Reviews in Medical Virology, volume 14, issue 2, pages 71-82 (issn: 1052-9276, eissn: 1099-1654, Copyright policy)
  • Publisher: John Wiley & Sons, Ltd.
Abstract Vaccination is the current strategy for control and prevention of severe rotavirus infections, a major cause of acute, dehydrating diarrhoea in young children worldwide. Public health interventions aimed at improving water, food and sanitation are unlikely adequately to control the disease. The development of vaccines against severe rotavirus diarrhoea is based upon homotypic or heterotypic protection provided against either a single common G serotype (monovalent vaccines) or against multiple serotypes (multivalent vaccines). Rotavirus strain surveillance has a high priority in disease control programmes worldwide. The continued identification of the mo...
free text keywords: Review Article, Review Articles, Typing, Vaccination, Reassortment, Disease, Rotavirus, medicine.disease_cause, medicine, Virology, Immunology, Serotype, Genotyping, Biology, Genotype
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