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Autonomous and Assisted Control for Synthetic Microbiology

Banderas, Alvaro; Le Bec, Matthias; Cordier, Céline; Hersen, Pascal;
Open Access
<p><strong>Abstract</strong></p> <p>The control of microbes and microbial consortia to achieve specific functions requires synthetic circuits that can reliably cope with internal and external perturbations. Circuits that naturally evolved to regulate biological functions are frequently robust to alterations in their parameters. As the complexity of synthetic circuits increases, synthetic biologists need to implement such robust control &ldquo;by design&rdquo;. This is especially true for intercellular signaling circuits for synthetic consortia, where robustness is highly desirable, but its mechanisms remain unclear. Cybergenetics, the interface between syntheti...
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Funded by
Control Engineering of Biological Systems for Reliable Synthetic Biology Applications
  • Funder: European Commission (EC)
  • Project Code: 766840
  • Funding stream: H2020
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