publication . Other literature type . Article . 2016

Stabilizing Effects Of Deep Eutectic Solvents On Alcohol Dehydrogenase Mediated Systems

Hassani, Fatima Zohra Ibn Majdoub; Lavandera, Ivan; Kreit, Joseph;
Open Access English
  • Published: 03 Oct 2016
  • Publisher: Zenodo
Abstract
This study explored the effects of different organic solvents, temperature, and the amount of glycerol on the alcohol dehydrogenase (ADH)-catalysed stereoselective reduction of different ketones. These conversions were then analyzed by gas chromatography. It was found that when the amount of deep eutectic solvents (DES) increases, it can improve the stereoselectivity of the enzyme although reducing its ability to convert the substrate into the corresponding alcohol. Moreover, glycerol was found to have a strong stabilizing effect on the ADH from <em>Ralstonia</em> sp. (<em>E. coli</em>/ RasADH). In the case of organic solvents, it was observed that the best conv...
Subjects
free text keywords: Alcohol dehydrogenases, DES, gas chromatography, RasADH.
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Zenodo
Other literature type . 2016
Provider: Datacite
ZENODO
Article . 2016
Provider: ZENODO
Zenodo
Other literature type . 2016
Provider: Datacite
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publication . Other literature type . Article . 2016

Stabilizing Effects Of Deep Eutectic Solvents On Alcohol Dehydrogenase Mediated Systems

Hassani, Fatima Zohra Ibn Majdoub; Lavandera, Ivan; Kreit, Joseph;