publication . Other literature type . Article . 1996

Neonatal Tolerance Revisited: Turning on Newborn T Cells with Dendritic Cells

J. P. Ridge; E. J. Fuchs; P. Matzinger;
  • Published: 22 Mar 1996
  • Publisher: American Association for the Advancement of Science (AAAS)
Abstract
For some time it has been thought that antigenic challenge in neonatal life is a tolerogenic rather than immunogenic event. Reexamination of the classic neonatal tolerance experiments of Billingham, Brent, and Medawar showed that tolerance is not an intrinsic property of the newborn immune system, but that the nature of the antigen-presenting cell determines whether the outcome is neonatal tolerance or immunization.
Subjects
Medical Subject Headings: chemical and pharmacologic phenomena
free text keywords: Multidisciplinary, Biology, Antigen, Cell, medicine.anatomical_structure, medicine, T lymphocyte, Antigen presentation, Immune tolerance, Immune system, Immunology
Related Organizations
Download fromView all 3 versions
ZENODO
Article . 1996
Provider: ZENODO
Science
Article
Provider: UnpayWall
Science
Article . 1996
Provider: Crossref
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue
publication . Other literature type . Article . 1996

Neonatal Tolerance Revisited: Turning on Newborn T Cells with Dendritic Cells

J. P. Ridge; E. J. Fuchs; P. Matzinger;