Immunity to Citrullinated Proteins in Rheumatoid Arthritis

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Klareskog, Lars; Rönnelid, Johan; Lundberg, Karin; Padyukov, Leonid; Alfredsson, Lars;

Antibodies to citrullinated proteins (ACPA), i.e., to peptides posttranslationally modified by the conversion of arginine to citrulline, are specific serological markers for rheumatoid arthritis (RA). Studies on anticitrulline immunity, summarized in this review, demons... View more
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