publication . Article . Other literature type . 2011

How does a hypha grow? The biophysics of pressurized growth in fungi

Lew, Roger R.;
Open Access
  • Published: 06 Jun 2011
Abstract
The mechanisms underlying the growth of fungal hyphae are rooted in the physical property of cell pressure. Internal hydrostatic pressure (turgor) is one of the major forces driving the localized expansion at the hyphal tip which causes the characteristic filamentous shape of the hypha. Calcium gradients regulate tip growth, and secretory vesicles that contribute to this process are actively transported to the growing tip by molecular motors that move along cytoskeletal structures. Turgor is controlled by an osmotic mitogen-activated protein kinase cascade that causes de novo synthesis of osmolytes and uptake of ions from the external medium. However, as discuss...
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Medical Subject Headings: fungi
free text keywords: General Immunology and Microbiology, Turgor pressure, Hypha, Biophysics, Hyphal growth, Hyphal tip, Tip growth, Osmolyte, Cell biology, Osmotic pressure, Hydrostatic pressure, Biology
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