Assessing brain immune activation in psychiatric disorders: clinical and preclinical PET imaging studies of the 18-kDa translocator protein

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van der Doef, Thalia F; Doorduin, Janine; van Berckel, Bart NM; Cervenka, Simon;
(2015)
  • Publisher: Springer Milan
  • Journal: volume 3,issue 6,pages449-460issn: 2281-5872, eissn: 2281-7565
  • Related identifiers: doi: 10.1007/s40336-015-0140-0, pmc: PMC5496979
  • Subject: Review Article | Neuroinflammation | TSPO | Psychiatry | Microglia | PET

Accumulating evidence from different lines of research suggests an involvement of the immune system in the pathophysiology of several psychiatric disorders. During recent years, a series of positron emission tomography (PET) studies have been published using radioligand... View more
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