Covalently-crosslinked mucin biopolymer hydrogels for sustained drug delivery

Article OPEN
Duffy , Connor; David , Laurent; Crouzier , Thomas;
(2015)
  • Publisher: Elsevier
  • Related identifiers: doi: 10.1016/j.actbio.2015.03.024, doi: 10.5281/zenodo.17922
  • Subject: paclitaxel | sustained release | Mucin hydrogel | polymyxin B | drug delivery | mucins | Amphiphile | mucus | hydrogel | [ CHIM.MATE ] Chemical Sciences/Material chemistry | Crosslinking | methacrylation | [ CHIM.POLY ] Chemical Sciences/Polymers

International audience; The sustained delivery of both hydrophobic and hydrophilic drugs from hydrogels has remained a challenge requiring the design and scalable production of complex multifunctional synthetic polymers. Here, we demonstrate that mucin glycoproteins, th... View more
Share - Bookmark