publication . Article . Other literature type . 2019

Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution.

S. Rotter; A. Beronius; A. R. Boobis; A. Hanberg; J. van Klaveren; M. Luijten; K. Machera; D. Nikolopoulou; H. van der Voet; J. Zilliacus; ...
Open Access English
  • Published: 10 Jan 2019
  • Country: Netherlands
Abstract
This article reviews the current legislative requirements for risk assessment of combined exposure to multiple chemicals via multiple exposure routes, focusing on human health and particularly on food-related chemicals. The aim is to identify regulatory needs and current approaches for this type of risk assessment as well as challenges of the implementation of appropriate and harmonized guidance at international level. It provides an overview of the current legal requirements in the European Union (EU), the United States and Canada. Substantial differences were identified in the legal requirements for risk assessment of combined exposure to multiple chemicals an...
Subjects
free text keywords: Cumulative risk assessment, chemical mixtures, pesticides, combined exposure, dietary exposure, harmonization, testing strategies, policy making, Biometris (PPO/PRI), Biometris, Cumulative risk assessment, chemical mixtures, combined exposure, dietary exposure, harmonization, pesticides, policy making, testing strategies, Toxicology, Legislation, Risk assessment, Environmental health, Biology, Human health
Funded by
EC| EuroMix
Project
EuroMix
EuroMix
  • Funder: European Commission (EC)
  • Project Code: 633172
  • Funding stream: H2020 | RIA
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publication . Article . Other literature type . 2019

Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution.

S. Rotter; A. Beronius; A. R. Boobis; A. Hanberg; J. van Klaveren; M. Luijten; K. Machera; D. Nikolopoulou; H. van der Voet; J. Zilliacus; ...