Immature monocytes recruited to the ischemic mouse brain differentiate into macrophages with features of alternative activation

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Miró-Mur, Francesc; Pérez-de Puig, Isabel; Ferrer-Ferrer, Maura; Urra, Xabier; Justicia, Carles; Chamorro, Angel; Planas, Anna M;

Acute stroke induces a local inflammatory reaction causing leukocyte infiltration. Circulating monocytes are recruited to the ischemic brain and become tissue macrophages morphologically indistinguishable from reactive microglia. However, monocytes are a heterogeneous p... View more
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