Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity

Article, Other literature type English OPEN
Kumar, A.; Ouyang, M.; Dries, K. van den; McGhee, E.J.; Tanaka, K.; Anderson, M.D.; Groisman, A.; Goult, B.T.; Anderson, K.I.; Schwartz, M.A.;

Integrin-dependent adhesions are mechanosensitive structures in which talin mediates a linkage to actin filaments either directly or indirectly by recruiting vinculin. Here, we report the development and validation of a talin tension sensor. We find that talin in focal ... View more
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