publication . Other literature type . Preprint . Article . 2020

Efficient molecule discrimination in electron microcopy through an optimized orbital angular momentum sorter

Troiani, Filippo; Rotunno, Enzo; Ravelli, Raimond; Peters, Peter; Karimi, Ebrahim; Grillo, Vincenzo;
Open Access
  • Published: 20 May 2020
  • Publisher: Zenodo
Abstract
We consider the problem of discriminating macromolecular structures in an electron microscope, through a specific beam shaping technique. Our approach is based on maximizing the which-molecule information extracted from the state of each electron. To this aim, the optimal observables are derived within the framework of quantum state discrimination, which allows one to fully account from the quantum character of the probe. We simulate the implementation of such optimal observable on a generalized orbital angular momentum (OAM) sorter and benchmark its performance against the best known real space approach.
Subjects
free text keywords: Q-sort, proteins, TEM
Funded by
EC| Q-SORT
Project
Q-SORT
QUANTUM SORTER
  • Funder: European Commission (EC)
  • Project Code: 766970
  • Funding stream: H2020 | RIA
Validated by funder
Communities
FET H2020FET OPEN: FET-Open research and innovation actions
FET H2020FET OPEN: QUANTUM SORTER
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Zenodo
Other literature type . 2020
Provider: Datacite
ZENODO
Preprint . 2020
Provider: ZENODO
Zenodo
Other literature type . 2020
Provider: Datacite
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