publication . Article . 2020

Multiple sclerosis: Excess of Cytoplasmic Steroid Receptors to Corresponding Hormones in the Oligodendrocytes

Ebbe Lundsgaard*;
Open Access English
  • Published: 03 Jul 2020
Abstract
Abstract An excess of zinc-enriched type 1 steroid receptors to matching steroid hormones may damage oligodendrocytes and cause central nervous system demyelination and multiple sclerosis. These receptors for vitamin D, estrogens, androgens, and other steroids can form cytoplasmic aggregates that occasionally release zinc in larger amounts, causing hyperphosphorylation of tau protein and degradation of the oligodendrocytes and the myelin sheath around the neurons.Postmenopausal women and older men with multiple sclerosis and a hereditary low sex hormone level matched by excess receptors may develop symptoms of Alzheimer’s. Six facts about multiple sclerosis were...
Subjects
free text keywords: Multiple-sclerosis; Oligodendrocytes; Steroid-receptors; Steroid-hormones; Vitamin-D; Estrogen. [Keywords]
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Article . 2020
Provider: ZENODO
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