publication . Article . 2020

Love at first taste: Activation in reward-related brain regions during single-trial naturalistic appetitive conditioning in humans

Anja Lender; Stephan F. Miedl; Frank H. Wilhelm; Miller J; Jens Blechert;
Open Access
  • Published: 15 Jun 2020
Palatable food can trigger appetitive responses, such as salivation and approach tendencies. Though evolutionarily functional, these conditioned responses can encourage overeating and obesity when food is abundant. The current study examines the neural correlates of 'denovo' Pavlovian appetitive conditioning, pairing one class of unknown objects (conditioned stimuli, CS) with their sweet taste (unconditioned stimulus, US) during a single trial. To do so, 23 participants consumed unknown (marzipan) objects of one particular color (CS+) while only interacting with control stimuli of different color and shape (CS-). After this single-trial conditioning procedure, p...
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Medical Subject Headings: digestive, oral, and skin physiology
free text keywords: Affective neuroscience, Appetitive conditioning, Food craving, Incentive salience, Caudate, Amygdala, Experimental and Cognitive Psychology, Behavioral Neuroscience, Functional magnetic resonance imaging, medicine.diagnostic_test, medicine, Food craving, Incentive salience, Overeating, Neural correlates of consciousness, Stimulus (physiology), Neuroscience, Amygdala, medicine.anatomical_structure, Craving, medicine.symptom, Psychology
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Funded by
EC| NewEat
Transdiagnostic views on eating disorders and obesity and new approaches for treatment
  • Funder: European Commission (EC)
  • Project Code: 639445
  • Funding stream: H2020 | ERC | ERC-STG
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