Sampling Strategies To Capture Single-Cell Heterogeneity

Article, Other literature type English OPEN
Satwik Rajaram; Heinrich, Louise E.; Gordan, John D.; Jayant Avva; Bonness, Kathy M.; Witkiewicz, Agnieszka K.; Malter, James S.; Atreya, Chloe E.; Warren, Robert S.; Lani F. Wu; Altschuler, Steven J.;
  • Publisher: Zenodo
  • Identifiers: doi: 10.5281/zenodo.841834, doi: 10.5281/zenodo.841835, doi: 10.1038/nmeth.4427
  • Subject: Lung Neoplasms | Biomarkers | Mental Health | Developmental Biology | Sampling | Adenocarcinoma | Neoplastic | Technology | Biological Sciences | Medical and Health Sciences | Gene Expression Regulation | 1.1 Normal biological development and functioning | Generic Health Relevance | Carcinoma | Cell Culture Techniques | Tumor | Cellular Heterogeneity | Non-Small-Cell Lung | Microscopy | Cell Line | Humans | Single-Cell Analysis

Advances in single-cell technologies have highlighted the prevalence and biological significance of cellular heterogeneity. A critical question is how to design experiments that faithfully capture the true range of heterogeneity from samples of cellular populations. Her... View more