publication . Other literature type . Article . 2019

DEVELOPMENT AND CHARACTERIZATION OF MICROPARTICLES OF RAZATRIPTAN BENZOATE DRUG CARRIER SYSTEM VIA NASAL ROUTE

Sunil T.Galatage1*, S.G.Killedar2, Anil Patil3, Swapnil Harale4, Y. R. Hundekar4;
Open Access
  • Published: 05 Mar 2019
  • Publisher: Zenodo
Abstract
Objective: Rizatriptan Benzoate is the 5H1 receptor agonist and used in treatment of migraine, cluster headache. The main objective is to develop ideal anti-migraine nasal mucoadhesive microparticles as local and systemic drug delivery system. Method: An attempt was made to formulate the nasal mucoadhesive microparticle of Rizatriptan Benzoate with excipients like mucoadhesive polymers i.e HPMC, ethyl cellulose etc., by using modified solvent evaporation method. And evaluated them for production yield, drug loading efficiency, surface morphology by SEM, drug content, particle size, <em>In-vitro</em> drug release studies. The release rates were studied using GRAP...
Subjects
free text keywords: Intra Nasal Mucoadhesive Microparticle, Rizatriptan Benzoate, Mucoadhesion Time, In-Vitro Drug Release Etc.
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Other literature type . 2019
Provider: Datacite
Zenodo
Other literature type . 2019
Provider: Datacite
ZENODO
Article . 2019
Provider: ZENODO
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publication . Other literature type . Article . 2019

DEVELOPMENT AND CHARACTERIZATION OF MICROPARTICLES OF RAZATRIPTAN BENZOATE DRUG CARRIER SYSTEM VIA NASAL ROUTE

Sunil T.Galatage1*, S.G.Killedar2, Anil Patil3, Swapnil Harale4, Y. R. Hundekar4;