publication . Article . Other literature type . 1993

Linear plasmids and chromosomes in bacteria

Hinnebusch, Joe; Tilly, Kit;
Open Access
  • Published: 01 Dec 1993 Journal: Molecular Microbiology, volume 10, pages 917-922 (issn: 0950-382X, eissn: 1365-2958, Copyright policy)
  • Publisher: Wiley
Abstract
Summary Linear plasmids and chromosomes were unknown in prokaryotes until recently but have now been found in spirochaetes, Gram-positive bacteria, and Gram-negative bacteria. Two structural types of bacterial linear DNA have been characterized. Linear plasmids of the spirochaete Borrelia have a covalently closed hairpin loop at each end and linear plasmids of the Gram-positive filamentous Streptomyces have a covalently attached protein at each end. Replicons with similar structures are more frequent in eukaryotic cells than in prokaryotes. Linear genomic structures are probably more common in bacteria than previously recognized, however, and some replicons may ...
Subjects
free text keywords: Molecular Biology, Microbiology, Plasmid, DNA replication, Spirochaete, biology.organism_classification, biology, Chromosome, Replicon, Bacteria, Genetics, DNA, chemistry.chemical_compound, chemistry, Bacterial cell structure
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publication . Article . Other literature type . 1993

Linear plasmids and chromosomes in bacteria

Hinnebusch, Joe; Tilly, Kit;