publication . Article . Other literature type . 2017

HPLC DETERMINATION OF FENBENDAZOLE AND IVERMECTIN SIMULTANEOUSLY IN BULK AND PHARMACEUTICAL DOSAGE FORMS

Battula Sreenivasa Rao, Mandapati Varaprasad Reddy*;
Open Access
  • Published: 25 May 2017
Abstract
In the present study, a simple, precise and accurate high performance liquid chromatography with photodiode array detector was developed for the simultaneous estimation of ivermectin & fenbendazole in bulk and tablet dosage forms. A Zorbax C8 column (250 cm × 4.6 mm × 5 μm) with mobile phase consisting of 0.1 M potassium dihydrogen orthophosphate and methanol (60:40 v/v) having pH 4.5 (adjusted with orthophosphoric acid) was used. The flow rate was 1.2 ml/min and the effluents were detected at 268 nm. The retention times of ivermectin and fenbendazole were found to be at 3.296 min and 7.257 min, respectively. The linearity of the selected drugs was obtained ...
Subjects
free text keywords: Ivermectin, fenbendazole, HPLC, Stability indicating, Assay
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ZENODO
Article . 2017
Provider: ZENODO
Zenodo
Other literature type . 2017
Provider: Datacite
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