Electron Leakage from the Mitochondrial NADPH-Adrenodoxin Reductase-Adrenodoxin-P450scc (Cholesterol Side Chain Cleavage) System

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Hanukoglu, I.; Rapoport, R.; Weiner, L.; Sklan, D.;

In electron (e-) transfer systems some e- may "leak" reducing O2 to superoxide radical. This study examined the sites and kinetics of e- leakage from the mitochondrial P450scc system. Adrenodoxin reductase alone oxidized NADPH reducing O2 to superoxide radical at a very... View more
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