LIN28 selectively modulates a subclass of let-7 microRNAs

Article, Other literature type English OPEN
Ustianenko, Dmytro; Chiu, Hua-Sheng; Treiber, Thomas; Weyn-Vanhentenryck, Sebastien M.; Treiber, Nora; Meister, Gunter; Sumazin, Pavel; Zhang, Chaolin;

LIN28 is a bipartite RNA-binding protein that post-transcriptionally inhibits the biogenesis of let-7 microRNAs to regulate development and influence disease states. However, the mechanisms of let-7 suppression remains poorly understood, because LIN28 recognition depend... View more
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