Development of a human physiologically based pharmacokinetic (PBPK) model for phthalate (DEHP) and its metabolites: A bottom up modeling approach

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R.P. Sharma; M. Schuhmacher; V. Kumar;
  • Related identifiers: doi: 10.1016/j.toxlet.2018.06.1217
  • Subject: MEHP | Human health risk assessment | IVIVE | DEHP | Endocrine disruptors | Pharmacokinetics | PBPK | Human biomonitoring
    mesheuropmc: endocrine system

DEHP exposure to human comes from different sources such as food, diet, cosmetics, toys, medical products, and food wraps. Recently, DEHP was categorized as non-persistent endocrine disrupting compounds (EDCs) by the world health organization (WHO). Rat experimental stu... View more
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