Magnetization transfer contrast imaging detects early white matter changes in the APP/PS1 amyloidosis mouse model

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Jelle Praet; Christian Bigot; Jasmien Orije; Maarten Naeyaert; Disha Shah; Zhenhua Mai; Pieter-Jan Guns; Annemie Van der Linden; Marleen Verhoye;
  • Publisher: Elsevier
  • Journal: NeuroImage : Clinical, volume 12, pages 85-92 (issn: 2213-1582, eissn: 2213-1582)
  • Publisher copyright policies & self-archiving
  • Identifiers: pmc: PMC4925888, doi: 10.1016/j.nicl.2016.06.014
  • Subject: Alzheimer's disease | R858-859.7 | Magnetic resonance imaging | Magnetization transfer contrast imaging | Computer applications to medicine. Medical informatics | Neurology. Diseases of the nervous system | Biology | RC346-429 | White matter | Regular Article | APP/PS1 | Human medicine
    mesheuropmc: mental disorders

Abstract: While no definitive cure for Alzheimer's disease exists yet, currently available treatments would benefit greatly from an earlier diagnosis. It has previously been shown that Magnetization transfer contrast (MTC) imaging is able to detect amyloid beta plaques ... View more
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