publication . Article . Other literature type . 1998

Toxoplasmosis of rats: a review, with considerations of their value as an animal model and their possible role in epidemiology

J.K Frenkel; Jitender P. Dubey;
Open Access
  • Published: 01 May 1998
  • Publisher: Elsevier BV
Abstract
We critically review and summarize information on the prevalence of Toxoplasma gondii infections in rats, mainly Rattus norvegicus, and their possible role as a source of infection for larger carnivores and omnivores. We also review information on immunology and natural resistance, contributing to the model value of rats in the analysis of human infection. Rats can be successfully infected with oocysts (sporozoites), tissue cysts (bradyzoites), and tachyzoites. Even adult rats, that are resistant to clinical toxoplasmosis, can be infected orally with a few oocysts or tissue cysts. Infections with tachyzoites of the RH strain are highly variable. Congenital trans...
Subjects
Medical Subject Headings: parasitic diseases
free text keywords: General Veterinary, Parasitology, Pregnancy, medicine.disease, medicine, Antibody titer, Antibody, biology.protein, biology, CATS, Toxoplasma gondii, biology.organism_classification, Bioassay, Toxoplasmosis, Virology, Epidemiology, medicine.medical_specialty
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