Mechanism of corticotropin and cAMP induction of mitochondrial cytochrome P450 system enzymes in adrenal cortex cells.
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- Subject:mesheuropmc: endocrine system | hormones, hormone substitutes, and hormone antagonists
We studied the kinetics of ACTH induction of mitochondrial P450scc, P450c11 and their electron transport proteins, adrenodoxin, and adrenodoxin reductase in bovine adrenal cortex cells in primary culture. The mRNA levels of these enzymes increase and reach a peak within... View more