publication . Article . Other literature type . 2017

DESIGN AND IN VITRO CHARACTERIZATION OF KETOPROFEN CORE IN CUP PULSATILE TABLETS FOR CHRONOMODULATED DRUG THERAPY.

Matta Nalini Krishna Reddy1, Suresh Bandari2;
Open Access
  • Published: 31 Mar 2017
Abstract
The aim of the present investigation is to intend, develop and evaluate a pulsatile drug delivery containing a core-in-cup based system of dry coated tablet of ketoprofen based on chronomodulated approach for management of Rheumatoid Arthritis. This pulsatile system contained a core tablet surrounded by an impermeable outer shell and top cover layer. Core tablet contained the active ingredient acting as reservoir, ethylcellulose was used to form an impermeable outer shell, the top cover layer contained different hydrophilic polymers like SodiumAlginate, HPMCK4M, Sodium carboxymethylcellulose with different concentrations. The formulations were evaluated for vari...
Subjects
free text keywords: Ketoprofen, Core-in-Cup Tablets, Hydrophilic Polymers, Chronomodulated Drug Delivery., Ketoprofen, Core-in-Cup Tablets, Hydrophilic Polymers, Chronomodulated Drug Delivery.
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Zenodo
Article . 2017
Provider: Datacite
Zenodo
Other literature type . 2017
Provider: Datacite
Zenodo
Article . 2017
Provider: Datacite
Zenodo
Other literature type . 2017
Provider: Datacite
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