publication . Article . Preprint . 2012

Angiogenesis in Chronic Obstructive Pulmonary Disease

Góralczyk, Barbara; Drela, Ewelina; Góralczyk, Krzysztof; Szczypiorska, Anna; Rość, Danuta;
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  • Published: 03 Apr 2012 Journal: Medical and Biological Sciences, volume 26 (issn: 1734-591X, Copyright policy)
  • Publisher: Uniwersytet Mikolaja Kopernika/Nicolaus Copernicus University
  • Country: Poland
Abstract
Angiogenesis is a very important process that occurs in both physiological and pathological states. The new blood vessels formation is characteristic for cancers, ischemic diseases and inflammatory diseases. The process is controlled by factors that stimulate and inhibit neovascularization. The next stages of the neovascularization are known as well as the role of the extracellular matrix, cells and cytokines/factors growth modulating this process. The cells of the endothelium and proangiogenic factors are the most important. The endothelial progenitor cells (EPCs), which origin from bone marrow, are the cells involved in angiogenesis. VEGF is the most important...
Subjects
free text keywords: Immunology, Molecular Cell Biology, Pharmacology, chronic obstructive pulmonary disease (COPD), pro- and antiangiogenic factors, vascular endothelial growth factor (VEGF), endothelial progenitor cells (EPCs), COPD, medicine.disease, medicine, Clinical research, Lung, medicine.anatomical_structure, Biomarker (medicine), Pathophysiology, Bioinformatics, Biology, Angiogenesis, Disease, Cancer
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