publication . 0044 . 2012

Dietary Fat and Sugar Induce Obesity and Impair Glucose Tolerance in Prepubertal Pigs

van Eyk, Gregory Ryan;
Open Access
  • Published: 30 Apr 2012
  • Publisher: Virginia Tech
A pig model of childhood obesity was used to study the effects of dietary energy on body adiposity, and blood parameters associated with impaired glucose clearance. Prepubertal female pigs weaned at 21 d of age were fed control (CON), refined sugar (SUG), fat (FAT), and sugar-fat (SUGFAT) diets in a completely randomized arrangement for 16 wk. Calories from fat were 8.9% for CON, 5.6% for SUG, 35.5% for FAT and 32.3% for SUGFAT. Calories from sugar were 36.0% for SUG and 30.7% for SUGFAT. Adding fat, sugar or both to diets increased (P < 0.003) calorie intake. Percentage body fat was higher (P < 0.0001) in all treatments compared to CON, and in SUGFAT and FA...
free text keywords: glucose tolerance test, whole body composition, obesity, diabetes, metabolic syndrome
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0044 . 2012
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