publication . Article . 2010

Use of Depot Medroxyprogesterone Acetate and Fracture Risk

Meier, Christian; Brauchli, Yolanda B.; Jick, Susan S.; Kraenzlin, Marius E.; Meier, Christoph R.;
  • Published: 01 Jan 2010
  • Publisher: The Endocrine Society
  • Country: Indonesia
Abstract
Depot medroxyprogesterone acetate (DMPA), which has a high rate of use among teenagers in Europe and the United States, has been associated with impaired bone mineral acquisition during adolescence and accelerated bone loss in later life. Studies on the association between DMPA use and fracture risk are limited.; We aimed at evaluating the relationship between use of hormonal contraceptives, specifically DMPA, and fracture risk.; We conducted a case-control analysis using the United Kingdom-based General Practice Research Database.; Participants were females aged 20-44 yr with an incident fracture diagnosis between 1995 and 2008.; Odds ratios (OR) with 95% confi...
Subjects
free text keywords: Clinical Biochemistry, Biochemistry, Endocrinology, Diabetes and Metabolism, Endocrinology, Biochemistry, medical, Internal medicine, medicine.medical_specialty, medicine, Medroxyprogesterone, medicine.drug, Odds ratio, Medroxyprogesterone acetate, Risk factor, Bone density, business.industry, business, Confidence interval, Population, education.field_of_study, education, Body mass index
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publication . Article . 2010

Use of Depot Medroxyprogesterone Acetate and Fracture Risk

Meier, Christian; Brauchli, Yolanda B.; Jick, Susan S.; Kraenzlin, Marius E.; Meier, Christoph R.;