publication . Doctoral thesis . 2002

Biocompatibility of orthopaedic implants on bone forming cells

Kapanen, A. (Anita);
Open Access English
  • Published: 22 Feb 2002
  • Publisher: University of Oulu
  • Country: Finland
Abstract
Abstract Reindeer antler was studied for its possible use as a bone implant material. A molecular biological study showed that antler contains a growth factor promoting bone formation. Ectopic bone formation assay showed that antler is not an equally effective inducer as allogenic material. Ectopic bone formation assay was optimised for biocompatibility studies of orthopaedic NiTi implants. Ti-6Al-4V and stainless steel were used as reference materials. The assay showed differences in bone mineral densities, with superior qualities in NiTi. The rate of endochondral ossification varied between the implants, NiTi ossicles had larger cartilage and bone areas than o...
Subjects
Medical Subject Headings: technology, industry, and agricultureequipment and supplies
free text keywords: biocompatible materials, bone morphogenetic proteins, cell death, focal adhesion, osteoblasts
Related Organizations
145 references, page 1 of 10

Bordji K, Jouzeau JY, Mainard D, Payan E, Delagoutte JP & Netter P (1996a) Evaluation of the effect of three surface treatments on the biocompatibility of 316L stainless steel using human differentiated cells. Biomaterials 17:491-500. [OpenAIRE]

Bordji K, Jouzeau JY, Mainard D, Payan E, Netter P, Rie KT, Stucky T & Hage-Ali M (1996b) Cytocompatibility of Ti-6Al-4V and Ti-5Al-2.5Fe alloys according to three surface treatments, using human fibroblasts and osteoblasts. Biomaterials 17:929-940. [OpenAIRE]

Boström M, Lane J, Berberian W, Missri A, Tomin E, Weiland A, Doty S, Glaser D & Rosen V (1995) Immunolocalization and expression of bone morphogenetic proteins 2 ans 4 in fracture healing. J Orthop Rel Res 13:357-367. [OpenAIRE]

Brånemark PI, Adell R, Breine U, Hansson BO, Lindström J & Ohlsson A (1969) Intra-osseous anchorage of dental prostheses. I. Experimental studies. Scand J Plast Reconstr Surg 3:81-100.

Brighton CT & Hunt RM (1991) Early histological and ultrastructural changes in medullary fracture callus. J Bone Joint Surg 73:832-847.

Bruinink A & Wintermantel E (2001) Grooves affect primary bone marrow but not osteoblastic MC3T3-E1 cell cultures. Biomaterials 22:2465-2473.

Brune D (1986) Metal release from dental biomaterials. Biomaterials 7:163-175.

Buehler WJ & Wang FE (1968) A summary of recent research on the Nitinol* alloys and their potential application in ocean engineering. Ocean Engineering 1:105-120. [OpenAIRE]

Cartana J, Arola L & Romeu A (1989) Characterization of the inhibition effect induced by nickel on glucose-6-phosphate dehydrogenase and glutathione reductase. Enzyme 41:1-5.

Castleman LS, Motzkin SM, Alicandri FP & Bonawit VL (1976) Biocompatibility of nitinol alloy as an implant material. J Biomed Mat Res 10:695-731. [OpenAIRE]

Celeste AJ, Iannazzi JA, Taylor RC, Hewick RM, Rosen V, Wang EA & Wozney JM (1990) Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone. Proc Natl Acad Sci U S A 87:9843-9847. [OpenAIRE]

Celeste AJ, Ross JL, Yamali N, & Wozney JM (1995) The molecular cloning of human bone morphogenetic proteins-10, -11, and -12, three new members of the transforming growth factor-beta superfamily. J Bone Miner Res 10:S336.

Chang LC & Read TA (1951) Trans AIME 191:47.

Chang SC, Hoang B, Thomas JT, Vukicevic S, Luyten FP et al. (1994) Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development. J Biol Chem 269:28227-28234.

Chapman D.I. (1975) Antlers - bone of contention. Mammal Rev 5:121-172.

145 references, page 1 of 10
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