Chronic lymphocytic leukemia: assessing pathogenesis and prognosis by modern molecular cytogenetic studies and microRNAs expression

Doctoral thesis Italian OPEN
Saccenti, Elena;
(2014)
  • Publisher: Università degli studi di Ferrara
  • Subject: leukemia | lymphocytic | MED/15 | chronic | MED/15 Malattie del sangue
    mesheuropmc: hemic and lymphatic diseases | immune system diseases

Chronic lymphocytic leukemia (CLL) is a B-cell clonal lymphoprolipherative disorder characterized by the accumulation of small lymphocytes in the peripheral blood, bone marrow and lymph nodes deriving from the transformation of CD5+ B-cell. Despite a homogeneou... View more
  • References (1)

    3.3 Next-generation sequencing in CLL ....................................................................................... 61 3.3.1 Ion Torrent PGM (Personal Genome Machine) ................................................................... 64 3.3.2 Methods and results ............................................................................................................ 66

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