publication . Bachelor thesis . 2011

Studium interakce cytochromů P450 s potravními karcinogeny

Brabencová, Eliška;
Restricted Czech
  • Published: 01 Jan 2011
  • Country: Czech Republic
Abstract
Humans are exposed to various carcinogens during their life. One of the main sources of carcinogens is a human diet which plays an important role in the cancer development. This bachelor thesis deals with carcinogens that are formed during a technological food processing or cooking of food - polycyclic aromatic hydrocarbons, heterocyclic amines and nitrosamines, then carcinogens produced by fungi - mycotoxins, and carcinogens that are produced by plants - safrole, estragole and pyrrolizidine alkaloids. Among numerous enzymes involved in metabolism of carcinogens, cytochromes P450 belong to the most important ones. These enzymes constitute a superfamily of haem-t...
Subjects
free text keywords: carcinogenesis; karcinogeneze; food carcinogens; potravní karcinogeny; cytochromy P450; cytochromes P450
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