publication . Bachelor thesis . 2014

Methods of Molecular Biology in Predictive Diagnostics of Her/neu in Stomach Cancer

Důra, Miroslav;
Restricted Czech
  • Published: 01 Jan 2014
  • Country: Czech Republic
Abstract
Stomach cancer is a malignant neoplastic disease, which is caused by malignant transformation of the gastric mucosal epithelium. Elderly patients are more frequently affected, the majority of the patients are males. Stomach cancer has some typical features like minor symptomatology and early metastasis founding. Nowadays, a mild decrease of incidence is registered. Treatment of stomach cancer depends on its location and stage. Because of its relative chemo- and radioresistance, surgical resection is the only one potentially curable method, although there is high number of recurrences. An amplification and overexpression of HER2 receptor is detected in approximat...
Subjects
Medical Subject Headings: skin and connective tissue diseases
free text keywords: Gastric cancer; amplifikace; neu receptor; Klíčová slova: Karcinom žaludku; HER2; imunohistochemie; in situ hybridization [Q-PCR; immunohistochemistry; amplification; in situ hybridizace; Key words]
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