Multidrug-resistance in rat colon-carcinoma cell-lines CC531, CC531^{mdr+}$ and cc531(rev)

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Gheuens, Eric; van der Heyden, Sylke; Elst, Hilde; Eggermont, Alexander; van Oosterom, Allan T.; de Bruijn, Ernst;

Abstract: A rat colon carcinoma cell line, CC531, was exposed to stepwise increasing concentrations of colchicine. A cell line, CC531mdr+, which grows in the presence of 0.2 muM of colchicine was obtained. A revertant cell line, CC531rev was isolated upon colchicine wit... View more
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