publication . Other literature type . Article . 2014

Are 20 human papillomavirus types causing cervical cancer?

Arbyn, Marc; Tommasino, Massimo; Depuydt, Christophe; Dillner, Joakim;
  • Published: 11 Nov 2014
  • Publisher: Wiley
  • Country: Belgium
Abstract
Abstract: In 2012, the International Agency for Research on Cancer concluded that there was consistent and sufficient epidemiological, experimental and mechanistic evidence of carcinogenicity to humans for 12 HPV types (HPV16, HPV18, HPV31, HPV33, HPV35, HPV39, HPV45, HPV51, HPV52, HPV56, HPV58 and HPV59) for cervical cancer. Therefore, these types were considered as 1A carcinogens. They all belong to the family of the -Papillomaviridae, in particular to the species 5 (HPV51), 6 (HPV56), 7 (HPV18, HPV39, HPV45, HPV59) and 9 (HPV16, HPV31, HPV33, HPV35, HPV52, HPV58). Less evidence is available for a thirteenth type (HPV68, 7), which is classified as a 2A carcino...
Subjects
free text keywords: Human medicine, Epidemiology, medicine.medical_specialty, medicine, Carcinogen, Carcinogenesis, medicine.disease_cause, Pathology, Biomarker (medicine), Pathological, Cancer, medicine.disease, Cervical cancer, Cyclin D1, business.industry, business
Funded by
EC| HPV-AHEAD
Project
HPV-AHEAD
Role of human papillomavirus infection and other co-factors in the aetiology of head and neck cancer in India and Europe
  • Funder: European Commission (EC)
  • Project Code: 282562
  • Funding stream: FP7 | SP1 | HEALTH
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