publication . Article . 2005

Expression of Major Histocompatibility Complex class II and costimulatory molecules in oral carcinomas in vitro

Villarroel, Mariana; Speight, Paul M.; Barrett, A. William;
Open Access Spanish
  • Published: 01 Jul 2005
  • Publisher: Sociedad Española de Medicina Oral
  • Country: Spain
Abstract
El descubrimiento de que el epitelio escamoso estratificado que cubre la mucosa oral podia expresar moleculas del Complejo Mayor de Histocompatibilidad clase II en varias condiciones patologicas de tipo inflamatorio abrio la posibilidad de que los queratinocitos orales sean celulas inmunologicamente activas, las cuales pueden funcionar con .celulas presentadoras de antigenos'ñ. Para una efectiva activacion de los linfocitos T, las celulas presentadoras de antigenos requieren, ademas de la expresion de moleculas del Complejo Mayor de Histocompatibilidad clase II, senales co-estimuladoras. El proposito del presente estudio fue determinar la expresion de moleculas ...
Subjects
free text keywords: CD40, CD80, CD86, Complejo Mayor de Histocompatibilidad, epitelio oral, carcinoma oral, Costimulatory molecules, Major Histocompatibility Complex, oral epithelium, oral squamous cell carcinoma, Odontología, Ciencias de la salud, UNESCO::CIENCIAS MÉDICAS
Related Organizations
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