publication . Other literature type . 2018


Garzón-Ospina, Diego; Buitrago, Sindy P.; Ramos, Andrea E.; Patarroyo, Manuel A.;
Open Access English
  • Published: 25 Jan 2018
<p>Parasite antigen genetic diversity represents a great obstacle when designing a vaccine against malaria caused by Plasmodium vivax. Selecting vaccine candidate antigens has been focused on those fulfilling a role in invasion and which are conserved, thus avoiding specific-allele immune responses. Most antigens described to date belong to the blood stage, thereby blocking parasite development within red blood cells, whilst studying antigens from other stages has been quite restricted. Antigens from different parasite stages are required for developing a completely effective vaccine; thus, pre-erythrocyte stage antigens able to block the first line of infection...
free text keywords: Genetics, Plasmodium vivax, genetic diversity, sporozoite, vaccine, natural selection, hepatocyte invasion
Download from
Other literature type . 2018
Provider: FigShare
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue