publication . Other literature type . 2018

Investigating the acute and long-term effects of traumatic brain injury on the immune and fibrinolytic system

MARIA DAGLAS;
Open Access English
  • Published: 04 Apr 2018
  • Publisher: Monash University
Abstract
Traumatic brain injury is a serious condition that results in long-term disability in most patients. This thesis investigated the early and long-term effects of the immune and fibrinolytic response (blood clot breakdown), and the link between these two systems after brain injury in mice. A unique discovery was that the chronic immune response, over a period of 8 months, directly contributes to a worse outcome after brain injury. We also found gender-specific differences occurring at the early stage of injury, that influence recovery, brain-related pathology and the immune response after brain injury, mediated by components of the fibrinolytic system.
Subjects
free text keywords: Inflammation, Neuroscience, Traumatic brain injury, Haematology, Immunology, Adaptive immunity, Fibrinolytic system, 110202 Haematology
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Other literature type . 2018
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http://dx.doi.org/10.4225/03/5...
Other literature type . 2018
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publication . Other literature type . 2018

Investigating the acute and long-term effects of traumatic brain injury on the immune and fibrinolytic system

MARIA DAGLAS;