publication . Other literature type . 2017

Theoretical and practical insights for anorexia nervosa and major depression: novel neurobiological targets for pharmacology and brain stimulation therapies

Keating, Charlotte;
  • Published: 22 Mar 2017
  • Publisher: Monash University
Abstract
Major Depression (MD) and Anorexia Nervosa (AN) often present co-morbidly and both share neurobiological abnormalities. MD presents up to 3 times as often in females than males and AN presents in up to 95% of females. In the illness phase, pathophysiological evidence indicates similar abnormalities in both clinical groups including; dysfunction in the serotonin system (5-hydroxytryptamine, 5-HT) (of which some abnormalities persist following recovery) and between 60-80% of patients in both groups present with significant hyperactivity of the hypothalamopituitary adrenal (HPA) axis. The first line treatment approach for MD involves modulation of the 5-HT system u...
Subjects
free text keywords: Uncategorized, stress, restricted access and full embargo, brain stimulation, anorexia nervosa, thesis(doctorate), 1959.1/476136, major depression, antidepressant, anterior cingulate cortex, ethesis-20110127-121719, neurocircuit, hpa axis, monash:63571, reward, 2011
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Other literature type . 2017
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http://dx.doi.org/10.4225/03/5...
Other literature type . 2017
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publication . Other literature type . 2017

Theoretical and practical insights for anorexia nervosa and major depression: novel neurobiological targets for pharmacology and brain stimulation therapies

Keating, Charlotte;