publication . Article . 2015

Moving towards a safe by design approach for ENM: Linking ENM relevant properties to toxicological concerns

T. Borges; M.J. Silva; H. Louro;
Open Access English
  • Published: 14 Sep 2015
  • Publisher: Elsevier/ EUROTOX
  • Country: Portugal
Abstract
Within the Safe by Design concept, the functionality of a material and its toxicity are considered in an integrated way. The central goal of this presentation is to discuss some fundamental principles of engineered nanomaterials (ENM) interactions with biological systems relevant to human exposure and biological responses. Major factors to consider in the ENM safe-by-design approach are surface modification to reduce the potential hazardous properties of target nanoparticles (NP), compatibility between NP coatings and their matrix, as well as biopersistence, considering the relevant exposure scenarios across the life cycle of the target NP and products. This is ...
Subjects
free text keywords: Genotoxicidade Ambiental, Nanomaterials, Safety, Risk assessment, Biology, Toxicology
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publication . Article . 2015

Moving towards a safe by design approach for ENM: Linking ENM relevant properties to toxicological concerns

T. Borges; M.J. Silva; H. Louro;