publication . Master thesis . 2012

Regional quantification of lung function in cystic fibrosis using hyperpolarized xenon-129 and chemical shift imaging

Fernandes, Carolina Campanha;
Open Access English
  • Published: 01 Jan 2012
  • Country: Portugal
Abstract
Tese de mestrado em Engenharia Biomédica e Biofísica (Radiações em Diagnóstico e Terapia), apresentada à Universidade de Lisboa, através da Faculdade de Ciências, 2012 Cystic fibrosis (CF) is a genetic disorder in which the defective gene causes the production of unusually thick and viscous mucus that builds-up in the airways, leading to impaired ventilation and infection of lung structures. Currently, there is a lack of methods capable of routinely assessing, in a regional manner, basic physiological processes that occur in the lung, such as pulmonary gas uptake-exchange. The technique described in this study makes use of hyperpolarized Xenon-129 (HP Xe-129) ga...
Subjects
free text keywords: Fibrose cística, Xénon-129 hiperpolarizado, Espectroscopia por ressonância magnética, Ventilação, Absorçãoe/ou troca de gases, Teses de mestrado - 2012
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