publication . Doctoral thesis . Article . 2011

Chronic obstructive pulmonary disease : a proteomics approach

Alexandre, Bruno Miguel Coelho;
Open Access English
  • Published: 01 Jan 2011
  • Country: Portugal
Abstract
Tese de doutoramento, Biologia (Biologia Molecular), Universidade de Lisboa, Faculdade de Ciências, 2012 Chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation that is not fully reversible even under bronchodilators effect, caused by a mixture of small airway disease – obstructive bronchiolitis – and parenchymal destruction – emphysema. At the present time, COPD is the fourth leading cause of death and its prevalence and mortality are expected to continue increasing in next decade. Spirometry is the most reproducible way to measure lung function and is nowadays the best tool to diagnose airflow limitation and, consequently, d...
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free text keywords: Doença pulmonar obstrutiva crónica, Proteómica, Biologia molecular, Teses de doutoramento - 2012
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