publication . Doctoral thesis . 2001

HIV-1 infection during pregnancy and in children : significance of HIV-1 variability and the placental barrier

Casper, Charlotte;
English
  • Published: 01 Jan 2001
  • Publisher: Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)
  • Country: Sweden
Abstract
With the global increase in human immunodeficiency virus 1 (HIV-1) infection in women of childbearing age, there has also been an alarming increase in the number of mother-to-child transmissions of HIV-1. Although antiretroviral therapy and Cesarian section have been demonstrated to significantly decrease the vertical transmission rate of , these interventions are not widely available in the developing world. Therefore, studies of the mechanisms of vertical transmission are important. This thesis was based on a prospective follow-up of HIV-1-infected patients, especially mothers and children in Sweden and in Cameroon. Coreceptor usage of the primary HIV-1 isolat...
Subjects
Medical Subject Headings: virus diseases
free text keywords: MEDICAL AND HEALTH SCIENCES, MEDICIN OCH HÄLSOVETENSKAP, biological phenotype, genetic subtype, chemokine receptor, coreceptor, mother- to-child transmission, placenta, disease progression, child, pregnancy
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