publication . Doctoral thesis . 1997

Immunochemical, biochemical and evolutionary studies on Micrurus nigrocinctus nigrocinctus venom toxins

Alape-Girón, Alberto;
English
  • Published: 01 Jan 1997
  • Publisher: Karolinska Institutet, false
  • Country: Sweden
Abstract
Immunochemical, biochemical and evolutionary studies on Micrurus nigrocinctus nigrocinctus venom toxins Monoclonal antibodies (MAbs) were produced against venom proteins of M. nigrocinctus nigrocinctus, the medically most important elapid of Central America. Affinity purified polyclonal antibodies and some of the MAbs were used to develop immunoassays for the quantitative deterrnination of M. n. nigrocinctus venom antigens in biological fluids. It was shown that these assays readily detect venoms from the the most important coral snakes of North and Central America at the level of nanograms. An ELISA-based non-radioactive assay was used to detect the nicotinic a...
Subjects
free text keywords: MEDICAL AND HEALTH SCIENCES, MEDICIN OCH HÄLSOVETENSKAP, Monoclonal antibody, Phospholipase A2, neurotoxin, myotoxin, protein evolution
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue