publication . Doctoral thesis . 2005

Pituitary autoantibodies in endocrine disorders

Bensing, Sophie;
English
  • Published: 01 Jan 2005
  • Publisher: Karolinska Institutet, Department of Molecular Medicine
  • Country: Sweden
Abstract
Autoimmune endocrine disorders are characterised by the development of autoantibodies to specific autoantigens in the target organs. Lymphocytic hypophysitis (LyH) is a disease characterised by inflammation of the pituitary gland, often resulting in hypopituitarism. The aetiology of LyH is considered to be autoimmune. However, only a few pituitary autoantigens have so far been identified. Reliable autoantibody markers are requested in the diagnostic procedure of LyH to avoid unnecessary surgical intervention. The aim of this study was to evaluate the occurrence of pituitary autoantibodies in patients with nonadenomatous pituitary disease and also to identify nov...
Subjects
free text keywords: MEDICAL AND HEALTH SCIENCES, MEDICIN OCH HÄLSOVETENSKAP, Lymphocytic hypophysitis, hypopituitarism, empty sella syndrome, APS 1, autoantibodies, autoantigen, Secretogranin II, TDRD6.
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