publication . Doctoral thesis . 2001

Experimental studies on xenograft rejection

Wu, Guosheng;
English
  • Published: 01 Jan 2001
  • Publisher: Karolinska Institutet, Department of Surgical Science
Abstract
The use of animal organs and tissues may provide a solution to the severe and worsening shortage of human grafts. The aims of the present experimental studies were to provide a better understanding of the rejection mechanisms and give new clues for prevention of xenorejection, thereby hopefully contributing to the development of clinical xenotransplantation. Guinea pig hearts transplanted into rats undergo hyperacute rejection (HAR) within a few minute& C6rats can not form the membrane attack complex. Guinea pig hearts transplanted into such rats are not hyperacutely rejected, but instead undergo delayed xenograft rejection (DXR) w...
Subjects
free text keywords: MEDICAL AND HEALTH SCIENCES, MEDICIN OCH HÄLSOVETENSKAP
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