publication . Doctoral thesis . 2016

Enhancement of human adipose-derived stem cell expansion and stability for clinical use

Krähenbühl, S. M.;
Open Access English
  • Published: 01 Jan 2016
  • Publisher: Université de Lausanne, Faculté de biologie et médecine
Abstract
Co-culture techniques associating both dermal fibroblasts and epidermal keratinocytes have shown to have better clinical outcome than keratinocyte culture alone for the treatment of severe burns. Since fat grafting has been shown to improve scar remodelling, new techniques such as cell-therapy-assisted surgical reconstruction with isolated and expanded autologous adipose-derived stem cells (ASCs) would be of benefit to increase graft acceptation. Therefore, integrating ASCs into standardized procedures for cultured skin grafting could be of benefit for the patient if cell quality and quantity could be maintained. The purpose of this study was to evaluate ASC pro...
Subjects
free text keywords: Adipose-derived stem cells, Cell stability, Co-culture, Fat grafting, Lipofilling, Burn treatment, Biological bandages
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