Retention of posttranscriptional spliceosomes in nuclear speckles until splicing completion.

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Girard, C.; Will, C.; Peng, J.; Makarov, E.; Kastner, B.; Lemm, I.; Urlaub, H.; Hartmuth, K.; Lührmann, R.;

There is little quantitative information regarding how much splicing occurs co-transcriptionally in higher eukaryotes, and it remains unclear where precisely splicing occurs in the nucleus. Here we determine the global extent of co- and post-transcriptional splicing in ... View more
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