CDKL5 Disorder: a Novel Therapeutic Strategy to Improve Brain Development in a Newly Generated CDKL5 ko Mouse Model

Doctoral thesis OPEN
De Franceschi, Marianna;

The cyclin-dependent kinase like-5 (CDKL5) disorder is a rare neurodevelopmental disease caused by mutations in the CDKL5 gene, located on the X-chromosome. The consequent unsuccessful CDKL5 protein expression in the nervous system leads to a severe encephalopathy, c... View more
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