Fluoxetine: a case history of its discovery and preclinical development
Mico, Juan A.
antidepressant, depression, fluoxetine, selective serotonin reuptake inhibitor, serotonin | antidepressant | depression | fluoxetine | selective serotonin reuptake inhibitor
Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS. Advances in drug...