publication . Other literature type . 2017

Brain in complex regional pain syndrome

Hotta, Jaakko;
Open Access English
  • Published: 19 Jun 2017
  • Publisher: Helsingin yliopisto
  • Country: Finland
Abstract
Complex regional pain syndrome (CRPS) causes disabling and severe limb pain that is difficult to treat. The pain typically increases during motor actions, but is present also at rest. The pathophysiology of CRPS is incompletely understood. Some of the symptoms suggest involvement of the central nervous system, and accordingly, patients have been shown to display alterations in, for instance, the primary sensorimotor cortex (SM1) and indications of neuroinflammation. More thorough pathophysiological knowledge of CRPS would help to develop better treatments and diagnostics. My thesis includes four studies exploring the cerebral basis of CRPS. All patients particip...
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